Specifications

1. Our fully automatic rigid-body linear registration algorithms have been successfully tested using:

• CT to CT • MRI to MRI • CT and MRI

• Ultrasound and CT • Ultrasound and MRI • PET and CT

Registration of two 40MB volumes (human brain images) requires approximately 13 seconds (dual 1.2 GHz Athlons, 1GB ram). Our automatic linear registration algorithms incorporate normalized cross-correlation and mutual information similarity metrics.

2. Our fully automatic nonlinear registration ("warping") algorithm has been successfully tested using:

• T1 MRI to T1 MRI human brain images

• T2 MRI to T2 MRI human brain images

Registration of two 40MB volumes (human brain images) requires approximately 6 minutes (dual 1.2 GHz Athlons, 1GB ram). The nonlinear algorithm is based upon maximization of the normalized cross correlation. Ref: IEEE Trans Med Imaging, 22(1):93-104, 2003.

All of our registration algorithms are multi-threaded making them ideal for use on multiple CPU computers

Abbreviations: MRI - Magnetic resonance image, CT - Computed tomography image, PET - Positron emission tomography